Ceftriaxone is third generation Cephalosporin antibacterial.
The antimicrobial spectrum covers susceptible gram positive, gram negative and some anaerobic pathogens.
Each Vial Contains:
Sterile Ceftriaxone Sodium U.S.P. equivalent to anhydrous Ceftriaxone 1.0 gm.
Ceftriaxone is indicated for the treatment of wide variety of infections caused by sensitive gram positive, gram negative and anaerobic organisms.
This drug has high potential application in septicemia, serious bone and joint infections, some lower respiratory tract infections, intra-abdominal infections and some soft tissue infections caused by sensitive pathogens.
Respiratory tract infections ( Broncho-pneumonia, Pneumonia)
Uro-genital tract infections (Metritis, Nephritis, Pyometra, Cystitis)
Visceral infections and peritonitis
Gastro-intestinal tract infections (Calf scourts, Enteritis, Diarrhoea)
Skin & Soft tissue infections
Post-operative bacterial infections
Ceftriaxone is primarily bactericidal in action. Its action results from inhibition of mucopeptide synthesis in the bacterial cell wall.
DOSAGE AND ADMINISTRATION:
5-6 mg/kg body weight Intramuscular, Subcutaneous or Intravenous.
After reconstitution with 9.6 ml of sterile water, each 1 ml of solution contains approximately 100 mg equivalent of Ceftriaxone.
Withdraw entire contents and dilute to the desired concentration with the appropriate diluent, if needed for intravenous infusion.
Ceftriaxone is compatible with 0.9% Sodium Chloride solution, 5% or 10% Dextrose solution, 5% Dextrose and 0.9% Sodium Chloride solution and 5% Dextrose and 0.45% Sodium Chloride solution, 1% Lidocaine without adrenaline.
The reconstituted solution should be used immediately after preparation.